Clinical translation of hyperpolarized Metabolic MR

Hyperpolarization by dissolution Dynamic Nuclear Polarization (dDNP) is a versatile method for making solutions of strongly polarized nuclear spins in small molecules. The method has enabled a range of in vivo and in vitro applications that otherwise would not be possible. In particular, clinical imaging is now a reality with hyperpolarized 13C-pyruvate. In this talk I will give an introduction to the method and the applications.


Jan graduated from Technical University of Denmark (DTU) in 1991 with a MscEE and PhD (1995). He has worked in both Industry (Amersham and GE) and in Academia and is now Centre Leader of the Centre for Hyperpolarsisation in Magnetic Resonance at DTU. In addition to Jan’s research on hyperpolarization, which has resulted in  the dissolution Dynamic Nuclear Polarization (DNP) method, enhancing the sensitivity of NMR signal over 10 000 fold,  he has made significant scientific contributions to electron paramagnetic resonance imaging (EPRI) and Overhauser magnetic resonance imaging (OMRI).   Jan has 28 patents/ patent applications and 108 journal articles and has been received a number of awards for his work in magnetic resonance.

If you would like to meet with Jan please contact Lorine Wilkinson - Phone: 3346 0364 or email: 

About CAI Seminar Series

The perfect opportunity to attend cutting-edge research presentations involving CAI researchers or collaborators, each Tuesday at 9:30am in the CAI Seminar Room, entry via CAI main doors, facing Wep Harris oval (see map).

If you would like weekly email notification for the seminar series or are interested in presenting, please contact Maria Moran.