Microimaging

MR microimaging (imaging at sub 100 micron in-plane resolution) is generally aimed to probe the microscopic properties of small samples. For biological samples, this involves studying tissue/cellular components, diffusion characteristics and biomarkers of certain diseases. In preclinical imaging, MR microimaging is important for testing new or existing imaging agents to evaluate the efficacy of therapeutic development in animal models. 

In non-biological studies, such as rheology, MR microimaging is important for studying the microscopic properties and behaviour of materials such as metals, concrete, wood, plastics, hydrogels and various polymeric compounds. In particular, it is important for studying a biopolymer's stability (pH, temperature) and ability to release small molecules (such as therapeutic agents) in a controlled manner.

The microimaging facility provides consultation, equipment, services and training, collaborative research, project development and contract work. For more information about using the CAI microimaging facilities, contact the Facility Manager.

White-matter fibretracts of mouse brain revealed using ex vivo diffusion weighted imaging and fibretracking. Data acquired and processed by Dr Nyoman Kurniawan during development of diffusion weighted imaging protocols.