Detection of brain dysfunction in Chronic Fatigue Syndrome using multimodal brain MRI
Dr Leighton Barnden
Imaging Consultant,
National Centre for Neuroimmunology and Emerging Diseases,
Menzies Health Institute Queensland, Griffith University, presents:
Detection of brain dysfunction in Chronic Fatigue Syndrome using multimodal brain MRI
Dr Leighton Barnden PhD, will present his exciting findings across 15 years' experience analysing brain MRI in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Initially structural MRI, including correlations with clinical measures, was used. More recently, functional magnetic resonance imaging (fMRI) and Diffusion Tensor Imaging (DTI) were included. Abnormalities in the brain stem were a feature of the results. A discussion of technical aspects will be included.
Bio: Dr Leighton Barnden works at Griffith University, as a medical scientist and research consultant at the National Centre for Neuroimmunology and Emerging Disease in Griffith's Menzies Health Institute Queensland. He began his career in nuclear medicine and over the last 25 years, has specialised in medical image processing.
Examples of Dr Barnden's notable studies include:
- Evidence in chronic fatigue syndrome for severity-dependent upregulation of prefrontal myelination that is independent of anxiety and depression
- Progressive Brain Changes in Patients With Chronic Fatigue Syndrome: A Longitudinal MRI Study
- Autonomic correlations with MRI are abnormal in the brainstem vasomotor centre in Chronic Fatigue Syndrome
- Medial prefrontal cortex deficits correlate with unrefreshing sleep in patients with chronic fatigue syndrome
- Decreased Connectivity and Increased Blood Oxygenation Level Dependent Complexity in the Default Mode Network in Individuals with Chronic Fatigue Syndrome
- Brain function characteristics of chronic fatigue syndrome: A task fMRI study
- Intra brainstem connectivity is impaired in chronic fatigue syndrome
- Mapping of pathological change in chronic fatigue syndrome using the ratio of T1- and T2-weighted MRI scans
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