High Resolution NMR Spectroscopy
Nuclear Magnetic Resonance (NMR) spectroscopy is a sophisticated, powerful and versatile analytical technique that underpins many key research fields. NMR has been used for many years for the quantitative analysis of solutions of single compounds or a mixture of compounds. Spectral databases exist that provide confirmation of identity and structure.
The Centre for Advanced Imaging has a range of NMR spectrometers at different field strengths. Our researchers have extensive experience with a wide-variety of NMR studies and are available to provide expert guidance with project planning, data analysis and optimisation.
Example applications include:
- Structure determination: the complete molecular structure and three dimensional conformation of complex biomolecules such as proteins and nucleic acids can be determined using a suite of NMR experiments. Structure elucidation of synthetic and natural products are regularly performed.
- Ligand screening: technologies for ligand screening have evolved for the detection and optimisation of drug candidates.
- Materials science: NMR is routinely used in material science research, for example, in polymer chemistry and food science.
- Metabolomics: metabolomics utilises the quantitative nature of NMR to analyse biological fluids containing many compounds simultaneously and is at the forefront in the identification of biomarkers for disease characterisation and progression.