Dr Saskia Bollmann
Postdoctoral Research Fellow, Centre for Advanced Imaging
The University of Queensland, presents:

Imaging of the pial arterial vasculature of the human brain in vivo using time-of-flight angiography at 7T

The pial arterial vasculature of the cerebrum consists of smaller distal arteries and arterioles that cover the cerebral cortical surface. It connects the branches of the three major supplying with the penetrating intracortical arterioles. Notably, the pial arterial vasculature is the only source of blood supply to the neocortex, and plays a central role in healthy hemodynamics measured using fMRI, as well as various vascular diseases. Imaging of pial arterial vessels in human using a non-invasive time-of-flight contrast is currently not performed, as the slow flow in these vessels is thought to diminish the available contrast.

In this presentation, I will revisit the fundamental theory of time-of-flight imaging, and adapt it to the regime of small pial arteries. I will show that, contrary to common belief, it is indeed possible to image these small pial vessels using high-resolution acquisitions.

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