Dr Min Chen
Postdoctoral Research Fellow
Centre for Advanced Imaging
+61 7 334 60363
Researcher biography
- To develop intravenous immunoglobulin (IVIg) as a novel antiepileptogenic treatment for temporal lobe epilepsy and to investigate the molecular and cellular mechanisms underlying the antiepileptogenic effect of IVIg.
- To investigate the regulation of epigenetic modifications, including microRNA and DNA methylation, by epileptogenic brain injury and to determine whether these epigenetic mechanisms are involved in epileptogenic gene regulation and contribute to the development of temporal lobe epilepsy.
Publications
Journal Articles
Chen, Min, Edwards, Stephen R., Maskey, Dhiraj, Woodruff, Trent M., Tomlinson, Stephen and Reutens, David (2023). Complement Component 5 (C5) Deficiency Improves Cognitive Outcome After Traumatic Brain Injury and Enhances Treatment Effects of Complement Inhibitors C1-Inh and CR2-Crry in a Mouse Model. Neurotrauma Reports, 4 (1), 663-681. doi: 10.1089/neur.2023.0024
Chen, Min, Tieng, Quang M., Du, Jiaxin, Edwards, Stephen R., Maskey, Dhiraj, Peshtenski, Emil and Reutens, David (2023). Effects of C1-INH treatment on neurobehavioral sequelae and late seizures after traumatic brain injury in a mouse model of controlled cortical impact. Neurotrauma Reports, 4 (1), 124-136. doi: 10.1089/neur.2022.0011
Chen, Min, Zhao, Qiong-Yi, Edson, Janette, Zhang, Zong Hong, Li, Xiang, Wei, Wei, Bredy, Timothy and Reutens, David C. (2020). Genome-wide microRNA profiling in brain and blood samples in a mouse model of epileptogenesis. Epilepsy Research, 166 106400, 106400. doi: 10.1016/j.eplepsyres.2020.106400
Chen, Min, Edwards, Stephen R. and Reutens, David C. (2020). Complement in the Development of Post-Traumatic Epilepsy: Prospects for Drug Repurposing. Journal of Neurotrauma, 37 (5), 692-705. doi: 10.1089/neu.2019.6942
Ziser, Laura, Meyer-Schell, Naja, Kurniawan, Nyoman D, Sullivan, Robert, Reutens, David, Chen, Min and Vegh, Viktor (2018). Utility of gradient recalled echo magnetic resonance imaging for the study of myelination in cuprizone mice treated with fingolimod. NMR in Biomedicine, 31 (3) e3877, e3877. doi: 10.1002/nbm.3877
Tieng, Quang M., Anbazhagan, Ashwin, Chen, Min and Reutens, David C. (2017). Mouse epileptic seizure detection with multiple EEG features and simple thresholding technique. Journal of Neural Engineering, 14 (6) 066006, 1-15. doi: 10.1088/1741-2552/aa8069
Chen, Min, Arumugam, Thiruma V., Leanage, Gayeshika, Tieng, Quang M., Yadav, Ashwin, Ullmann, Jeremy F. P., She, David T., Truong, Vy, Ruitenberg, Marc J. and Reutens, David C. (2017). Disease-modifying effect of intravenous immunoglobulin in an experimental model of epilepsy. Scientific Reports, 7 (1) 40528, 40528. doi: 10.1038/srep40528
Brinkmann, Benjamin H, Wagenaar, Joost, Abbot, Drew, Adkins, Phillip, Bosshard, Simone, Chen, Min, Tieng, Quang M., He, Jialune, MunËœoz-Almaraz, F. J., Botella-Rocamora, Paloma, Pardo, Juan, Zamora-Martinez, Francisco, Hills, Michael, Wu, Wei, Korshunova, Iryna, Cukierski, Will, Vite, Charles, Patterson, Edward E., Litt, Brian and Worrell, Gregory A. (2016). Crowdsourcing reproducible seizure forecasting in human and canine epilepsy. Brain, 139 (Pt 6), 1713-22. doi: 10.1093/brain/aww045
Tieng, Quang M., Kharatishvili, Irina, Chen, Min and Reutens, David C. (2016). Mouse EEG spike detection based on the adapted continuous wavelet transform. Journal of Neural Engineering, 13 (2) 026018, 026018. doi: 10.1088/1741-2560/13/2/026018
O'Leary, Conor J., Bradford, DanaKai, Chen, Min, White, Amanda, Blackmore, Daniel G. and Cooper, Helen M. (2014). The Netrin/RGM receptor, neogenin, controls adult neurogenesis by promoting neuroblast migration and cell cycle exit. Stem Cells, 33 (2), 503-514. doi: 10.1002/stem.1861
Dong, Haiyan, Chen, Min, Rahman, Shafiur, Parekh, Harendra S., Cooper, Helen M. and Xu, Zhi Ping (2014). Engineering small MgAl-layered double hydroxide nanoparticles for enhanced gene delivery. Applied Clay Science, 100 (C), 66-75. doi: 10.1016/j.clay.2014.04.028
Chen, Min, Helen Cooper, Zhou, Ji Zhi, Bartlett, Perry F. and Xu, Zhi Ping (2013). Reduction in the size of layered double hydroxide nanoparticles enhances the efficiency of siRNA delivery. Journal of Colloid and Interface Science, 390 (1), 275-281. doi: 10.1016/j.jcis.2012.09.033
Zhu, Yian, Li, Zhen, Chen, Min, Cooper, Helen, Lu, Gao Qing (Max) and Xu, Zhi Ping (2013). One-pot preparation of highly fluorescent cadmium telluride/cadmium sulfide quantum dots under neutral-pH condition for biological applications. Journal of Colloid and Interface Science, 390 (1), 3-10. doi: 10.1016/j.jcis.2012.08.003
Zhu, Yian, Li, Zhen, Chen, Min, Cooper, Helen M. and Xu, Zhi Ping (2013). Tuning core-shell SiO2@CdTe@SiO2 fluorescent nanoparticles for cell labeling. Journal of Materials Chemistry B, 1 (17), 2315-2323. doi: 10.1039/c3tb20202j
Wong, Yunyi, Cooper, Helen M., Zhang, Kai, Chen, Min, Bartlett, Perry and Xu, Zhi Ping (2012). Efficiency of layered double hydroxide nanoparticle-mediated delivery of siRNA is determined by nucleotide sequence. Journal of Colloid and Interface Science, 369 (1), 453-459. doi: 10.1016/j.jcis.2011.12.046
Zhu, Lin, Ji, Xiang-jun, Wang, Han-dong, Pan, Hao, Chen, Min and Lu, Ting-jia (2012). Zinc neurotoxicity to hippocampal neurons in vitro induces ubiquitin conjugation that requires p38 activation. Brain Research, 1438, 1-7. doi: 10.1016/j.brainres.2011.12.031
Zhu, Yian, Li, Zhen, Chen, Min, Cooper, Helen M., Lu, Gao Qing (Max) and Xu, Zhi Ping (2012). Synthesis of robust sandwich-like SiO2@CdTe@SiO2 fluorescent nanoparticles for cellular imaging. Chemistry of Materials, 24 (3), 421-423. doi: 10.1021/cm2033417
Wong, Yunyi, Markham, Kathryn, Xu, Zhi Ping, Chen, Min, Liu, Gao Qing (Max), Bartlett, Perry F. and Cooper, Helen M. (2010). Efficient delivery of siRNA to cortical neurons using layered double hydroxide nanoparticles. Biomaterials, 31 (33), 8770-8779. doi: 10.1016/j.biomaterials.2010.07.077
Chen, Min, Cheng, Qian, Cheng, Xue-Wen, Lu Ting-Jia, Liu, Han-Xing, Jia, Jie-Min, Zhang, Chi, Xu, Li and Xiong, Zhi-Qui (2009). Zn2+ mediates ischemia-induced impairment of the ubiquitin-proteasome system in the rat hippocampus. Journal of Neurochemistry, 111 (5), 1094-1103. doi: 10.1111/j.1471-4159.2009.06401.x
Chen, Min, Lu, Ting-Jia, Chen, Xiao-Jing, Zhou, Yang, Chen, Qian, Feng, Xiao-Yan, Xu, Li, Duan, Wen-Hu and Xiong, Zhi-Qi (2008). Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance. Stroke, 39 (11), 3042-3048. doi: 10.1161/STROKEAHA.108.521898
Zhu, Lin, Yan, Wei, Qi, Meng, Hu, Ze Lan, Lu, Ting Jia, Chen, Min, Zhou, Jin, Hang, Chun Hua and Shi, Ji Xin (2007). Alterations of pulmonary zinc homeostasis and cytokine production following traumatic brain injury in rats. Annals of Clinical and Laboratory Science, 37 (4), 356-361.
Chen, Min, Wang, Yao, Liu, Yong, Hou, Xiao-Yu, Zhang, Quan-Guang, Meng, Fan-Jie and Zhang, Guang-Yi (2003). Possible mechanisms underlying the protective effects of SY-21, an extract of a traditional Chinese herb, on transient brain ischemia/reperfusion- induced neuronal death in rat hippocampus. Brain Research, 989 (2), 180-186. doi: 10.1016/S0006-8993(03)03331-6
Chen, Min, Hou, XiaoYu and Zhang, GuangYi (2003). Tyrosine kinase and tyrosine phosphatase participate in regulation of interactions of NMDA receptor subunit 2A with Src and Fyn mediated by PSD-95 after transient brain ischemia. Neuroscience Letters, 339 (1), 29-32. doi: 10.1016/S0304-3940(02)01439-8
Hou, Xiao-Yu, Zhang, Guang-Yi, Yan, Jing-Zhi, Chen, Min and Liu, Yong (2002). Activation of NMDA receptors and L-type voltage-gated calcium channels mediates enhanced formation of Fyn-PSD95-NR2A complex after transient brain ischemia. Brain Research, 955 (1-2), 123-132. doi: 10.1016/S0006-8993(02)03376-0