Development of architectural polymers for nanomedicine: Design, synthesis and preclinical evaluation of nanomaterials for molecular imaging and drug delivery.
Assoc Prof Thurecht’s research focusses on the development of polymer and nanoparticle-based devices for nanomedicine. For polymers to be truly effective in nanomedicine, they must incorporate new therapies while maintaining their physical and chemical integrity. This can only be achieved by developing a strong understanding of the fundamental properties of the nanomaterial-delivery system, in addition to identifying and successfully delivering new therapies. Central to the development of these future therapeutic platforms, is the field of theranostics, where molecular imaging plays a key role in understanding the dynamics of polymeric nanomedicines. Assoc Prof Thurecht’s team works across the boundaries of chemistry and materials, biology and imaging science to probe how nanomaterial properties affect their function in living animals.
Keywords: Molecular imaging, Polymer chemistry, multimodal imaging, theranostics, drug delivery
See the Thurecht laboratory page for current group members.
|Magnetic Resonance Imaging Switches as Theranostic Agents|
|Nanomedicine for treating breast cancer: development of multi-therapeutic agents|
|Stimuli responsive switches utilising contrast agent modulated magnetic resonance imaging (MRI)|
Immuno-polymeric drugs for prostate cancer therapy
NHMRC Project Grant
Imaging tumour distribution of a polymeric drug delivery platform in vivo by PET-MRI
ARC Centre of Excellence
ACRF Facility for Molecular Imaging Agents in Cancer
Australian Cancer Research Foundation