Dr Karine Mardon is the Facility Manager for the preclinical PET/CT for the Queensland Node of the National Imaging Facility (NIF) as part of the National Collaborative Research Infrastructure Scheme (NCRIS), based at the Centre for Advanced Imaging, The University of Queensland. Current research projects include:
- Study of the metabolism of non-steroidal anti-inflammatory drugs (NSAID) in vivo using different animal models.
- Evaluation of drugs developed for the study of movement disorders using PET and SPECT imaging.
- Evaluation of radiolabelled peripheral benzodiazepine receptor ligands as markers of neurodegeneration and tumor occurrence.
- Effects of Streptozotocin-induced diabetes on neuronal sigma receptors in the rat brain and study of myocardial muscarinic receptors using I-123 N-methyl-4-iododexetimide
- Study of (+)-2-[123I]A-69024 as potential radioligand for in vivo studies of dopamine D1 receptors.