Associate Professor Horst Schirra
Honorary Associate Professor
Centre for Advanced Imaging
Associate Professor
Griffith University
+61 7 334 60346
Researcher biography
Dr Schirra is one of the leaders of NMR-based metabolomics in Australia. He studied Chemistry at the Johann-Wolfgang-Goethe University in Frankfurt, Germany, and received his PhD in Biochemistry from the Swiss Federal Institute of Technology (ETH) Zurich (Switzerland). In 1999, he joined the University of Queensland, where he was awarded a Postdoctoral Fellowship of the Australian Research Council and a prestigious Queensland Smart State Fellowship. In 2009, Dr Schirra became Lecturer in the School of Chemistry and Molecular Biosciences at UQ, and in 2012 he joined UQ's Centre for Advanced Imaging, where he led a multidisciplinary research program in Metabolic Systems Biology and administered the Centre’s facility for NMR-based metabolomics. Dr Schirra joined the School of Environment and Science - Chemical Sciences at Griffith University in July 2021.
Dr Schirra is a Director of the Metabolomics Society, Board Member of the Australian and New Zealand Society for Magnetic Resonance, and committee member of the Australian and New Zealand Metabolomics Network. He was Co-chair of the 13th International Conference of the Metabolomics Society in Brisbane 2017. He is an editorial board member of the journal Metabolites, and regional editor of Current Metabolomics.
Dr Schirra's main field of research is Metabolic Systems Biology. He uses NMR-based metabolomics to investigate the basic principles of metabolic regulation and the role they play in fundamental biological processes, environmental change, and in the development of disease, especially obesity and cancer. His research aims to integrate metabolomics with other –omics methods and metabolic simulations.
- NMR-based metabolomics and analytical systems biology using nuclear magnetic resonance (NMR) spectroscopy and other biochemical and biophysical techniques to understand how external triggers, such as drugs, illness, mutations etc., influence and change the metabolism of a subject. Pushing the boundaries of NMR-based metabolomics by integrating the technique with genomic and proteomic methods and by expanding the toolbox of computational methods to analyse metabolomic data.
- Metabolic regulation: characterising the role of the enzyme dihydrolipoamide dehydrogenase in metabolic regulation.
- Clinical diagnosis: Applying NMR-based metabolomics to improve the understanding of metabolism in health and disease and to improve diagnosis. Projects include: (1) development of obesity and related diseases, (2) diagnosis of prostate cancer, (3) investigating dietary intervention in epilepsy.
- Environmental research: the application of NMR-based metabolomics and systems biology in environmental research, specifically food security and livestock science.
PhD and MPhil Supervision
- View current and completed supervisions on UQ Researchers.
Book Chapters
Fyfe, Selina, Schirra, Horst Joachim, Rychlik, Michael, Smyth, Heather E. and Sultanbawa, Yasmina (2022). Australian Green Plum (
Buchanania obovata
). Handbook of Phytonutrients in Indigenous Fruits and Vegetables. (pp. 219-227) GB: CABI. doi: 10.1079/9781789248067.0014
Hattwell, Jake P. N., Hastings, Janna, Casanueva, Olivia, Schirra, Horst Joachim and Witting, Michael (2020). Using genome-scale metabolic networks for analysis, visualization, and integration of targeted metabolomics data. Computational methods and data analysis for metabolomics. (pp. 361-386) edited by Shuzhao Li. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0239-3_18
Schirra, Horst Joachim and Craik, David J. (2019). Overview of NMR in the Pharmaceutical Sciences. Modern Magnetic Resonance. (pp. 1195-1202) Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/1-4020-3910-7_128
Schirra, Horst Joachim and Ford, Pauline J. (2017). NMR-based metabolomics of oral biofluids. Oral biology: molecular techniques and applications. (pp. 79-105) New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-6685-1_5
Roberts, Matthew J., Schirra, Horst, Lavin, Martin F. and Gardiner, Robert A. (2014). NMR-based metabolomics: global analysis of metabolites to address problems in prostate cancer. Cervical, Breast and Prostate Cancer. (pp. 1-43) edited by iConcept Press. Tokwawan, Kowloon, Hong Kong: iConcept Press.
Schirra, H. J. and Craik, D. J. (2006). Overview of NMR in the Pharmaceutical Sciences. Modern Magnetic Resonance Part 2: Applications in Medical and Pharmaceutical Sciences. (pp. 1177-1184) edited by Graham A. Webb. Netherlands: Springer.
Schirra, Horst Joachim, Mühlhahn, Peter and Holak, Tad (1998). NMR Spektroskopie von Biomolekülen in Lösung. Bioanalytik. (pp. 371-411) edited by Friedrich Lottspeich and Haralabos Zorbas. Heidelberg, Germany: Spektrum Akademischer Verlag.
Journal Articles
Phan, Minh-Duy, Schirra, Horst Joachim, Nhu, Nguyen Thi Khanh, Peters, Kate M., Sarkar, Sohinee, Allsopp, Luke P., Achard, Maud E. S., Kappler, Ulrike and Schembri, Mark A. (2024). Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant
Escherichia coli
ST131. mBio, 15 (3), e0338823. doi: 10.1128/mbio.03388-23
Daubney, Emily R., D’Urso, Shannon, Cuellar-Partida, Gabriel, Rajbhandari, Dorrilyn, Peach, Elizabeth, de Guzman, Erika, McArthur, Colin, Rhodes, Andrew, Meyer, Jason, Finfer, Simon, Myburgh, John, Cohen, Jeremy, Schirra, Horst Joachim, Venkatesh, Balasubramanian and Evans, David M. (2024). A Genome-Wide Association Study of Serum Metabolite Profiles in Septic Shock Patients. Critical Care Explorations, 6 (1) ARTN e1030, e1030. doi: 10.1097/cce.0000000000001030
Fyfe, Selina, Smyth, Heather E., Schirra, Horst Joachim, Rychlik, Michael, Sultanbawa, Yasmina and Kurniawan, Nyoman D. (2023). Physical properties and magnetic resonance imaging of the Australian green plum (Buchanania obovata) through maturity and ripening and across locations. Postharvest Biology and Technology, 205 112494, 1-15. doi: 10.1016/j.postharvbio.2023.112494
Fyfe, Selina, Hong, Hung, Schirra, Horst Joachim, Smyth, Heather E., Sultanbawa, Yasmina and Rychlik, Michael (2022). Folate vitamers in the Australian green plum: through growth and ripening and across locations. Frontiers in Nutrition, 9 1006393, 1006393. doi: 10.3389/fnut.2022.1006393
Fyfe, Selina, Schirra, Horst Joachim, Rychlik, Michael, van Doorn, Annemarie, Tinngi, Ujang, Sultanbawa, Yasmina and Smyth, Heather E (2022). Future flavours from the past: sensory and nutritional profiles of green plum (Buchanania obovata), red bush apple (Syzygium suborbiculare) and wild peach (Terminalia carpentariae) from East Arnhem Land, Australia. Future Foods, 5 100136, 100136. doi: 10.1016/j.fufo.2022.100136
Hosmer, Jennifer, Nasreen, Marufa, Dhouib, Rabeb, Essilfie, Ama-Tawiah, Schirra, Horst Joachim, Henningham, Anna, Fantino, Emmanuelle, Sly, Peter, McEwan, Alastair G. and Kappler, Ulrike (2022). Access to highly specialized growth substrates and production of epithelial immunomodulatory metabolites determine survival of Haemophilus influenzae in human airway epithelial cells. PLoS Pathogens, 18 (1) e1010209, e1010209. doi: 10.1371/journal.ppat.1010209
Fyfe, Selina, Smyth, Heather E., Schirra, Horst Joachim, Rychlik, Michael and Sultanbawa, Yasmina (2022). The Framework for Responsible Research With Australian Native Plant Foods: A Food Chemist's Perspective. Frontiers in Nutrition, 8 738627, 738627. doi: 10.3389/fnut.2021.738627
Simpson, Joshua D., Currin-Ross, Denni L., Ediriweera, Gayathri R., Schirra, Horst Joachim, Fletcher, Nicholas L., Bell, Craig A., Arno, Maria C. and Thurecht, Kristofer J. (2021). Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes. Nanomaterials, 11 (7) 1745, 1-18. doi: 10.3390/nano11071745
Currin-Ross, Denni, Husdell, Luke, Pierens, Gregory K., Mok, Nicholas E., O'Neill, Scott L., Schirra, Horst Joachim and Brownlie, Jeremy C. (2021). The metabolic response to infection with Wolbachia implicates the insulin/insulin-like-growth factor and hypoxia signaling pathways in Drosophila melanogaster. Frontiers in Ecology and Evolution, 9 623561, 1-16. doi: 10.3389/fevo.2021.623561
Fyfe, Selina, Smyth, Heather E., Schirra, Horst Joachim, Rychlik, Michael and Sultanbawa, Yasmina (2020). The nutritional potential of the native Australian green plum (Buchanania obovata) compared to other Anacardiaceae fruit and nuts. Frontiers in Nutrition, 7 600215, 600215. doi: 10.3389/fnut.2020.600215
López-López, Nahikari, Euba, Begoña, Hill, Julian, Dhouib, Rabeb, Caballero, Lucı A, Leiva, José, Hosmer, Jennifer, Cuesta, Sergio, Ramos-Vivas, José, Díez-Martínez, Roberto, Schirra, Horst Joachim, Blank, Lars M., Kappler, Ulrike and Garmendia, Junkal (2020). Haemophilus influenzae glucose catabolism leading to production of the immunometabolite acetate has a key contribution to the host airway-pathogen interplay. ACS Infectious Diseases, 6 (3), 406-421. doi: 10.1021/acsinfecdis.9b00359
Pinu, Farhana R., Beale, David J., Paten, Amy M., Kouremenos, Konstantinos, Swarup, Sanjay, Schirra, Horst J. and Wishart, David (2019). Systems biology and multi-omics integration: viewpoints from the metabolomics research community. Metabolites, 9 (4) 76, 76. doi: 10.3390/metabo9040076
Muda, Noor Marian, Nasreen, Marufa, Dhouib, Rabeb, Hosmer, Jennifer, Hill, Julian, Mahawar, Manish, Schirra, Horst Joachim, McEwan, Alastair G. and Kappler, Ulrike (2019). Metabolic analyses reveal common adaptations in two invasive Haemophilus influenzae strains. Pathogens and Disease, 77 (2) ftz015. doi: 10.1093/femspd/ftz015
Kwan, Ann H., Mobli, Mehdi, Schirra, Horst J., Wilson, Jennifer C. and Jones, Oliver A. H. (2019). Video with impact: access to the world's Magnetic-Resonance experts for the scientific-education community. Journal of Chemical Education, 96 (1), 159-164. doi: 10.1021/acs.jchemed.8b00523
Witting, Michael, Hastings, Janna, Rodriguez, Nicolas, Joshi, Chintan J., Hattwell, Jake P. N., Ebert, Paul R., van Weeghel, Michel, Gao, Arwen W., Wakelam, Michael J. O., Houtkooper, Riekelt H., Mains, Abraham, Le Novère, Nicolas, Sadykoff, Sean, Schroeder, Frank, Lewis, Nathan E., Schirra, Horst-Joachim, Kaleta, Christoph and Casanueva, Olivia (2018). Modeling meets metabolomics— the WormJam consensus model as basis for metabolic studies in the model organism Caenorhabditis elegans. Frontiers in Molecular Biosciences, 5 (NOV) 96, 96. doi: 10.3389/fmolb.2018.00096
Martinez-Fernandez, Gonzalo, Duval, Stephane, Kindermann, Maik, Schirra, Horst J., Denman, Stuart E. and McSweeney, Christopher S. (2018). 3-NOP vs. halogenated compound: methane production, ruminal fermentation and microbial community response in forage fed cattle. Frontiers in Microbiology, 9 (AUG) 1582, 1582. doi: 10.3389/fmicb.2018.01582
Hastings, Janna, Mains, Abraham, Artal-Sanz, Marta, Bergmann, Sven, Braeckman, Bart P., Bundy, Jake, Cabreiro, Filipe, Dobson, Paul, Ebert, Paul, Hattwell, Jake, Hefzi, Hooman, Houtkooper, Riekelt H., Jelier, Rob, Joshi, Chintan, Kothamachu, Varun B., Lewis, Nathan, Lourenço, Artur Bastos, Nie, Yu, Norvaisas, Povilas, Pearce, Juliette, Riccio, Cristian, Rodriguez, Nicolas, Santermans, Toon, Scarcia, Pasquale, Schirra, Horst Joachim, Sheng, Ming, Smith, Reuben, Suriyalaksh, Manusnan, Towbin, Benjamin ... Casanueva, Olivia (2017). WormJam: A consensus C. elegans Metabolic Reconstruction and Metabolomics Community and Workshop Series. Worm, 6 (2), e1373939-00. doi: 10.1080/21624054.2017.1373939
Roberts, M.J., Richards, R.S., Chow, C.W.K., Buck, M., Yaxley, J., Lavin, M.F., Schirra, H.J. and Gardiner, R.A. (2017). Seminal plasma enables selection and monitoring of active surveillance candidates using nuclear magnetic resonance-based metabolomics: A preliminary investigation. Prostate International, 5 (4), 149-157. doi: 10.1016/j.prnil.2017.03.005
Roberts, Matthew J., Hattwell, Jake P. N., Chow, Clement W. K., Lavin, Martin, Pierens, Gregory K., Gardiner, Robert A. and Schirra, Horst Joachim (2016). Tartrate inhibition of prostatic acid phosphatase improves seminal fluid metabolite stability. Metabolomics, 12 (11) 162, 162.1-162.14. doi: 10.1007/s11306-016-1102-x
Roberts, Matthew J., Yaxley, John W., Coughlin, Geoffrey D., Gianduzzo, Troy R. J., Esler, Rachel C., Dunglison, Nigel T., Chambers, Suzanne K., Medcraft, Robyn J., Chow, Clement W. K., Schirra, Horst Joachim, Richards, Renee S., Kienzle, Nicholas, Lu, Macy, Brereton, Ian, Samaratunga, Hema, Perry-Keene, Joanna, Payton, Diane, Oyama, Chikara, Doi, Suhail A., Lavin, Martin F. and Gardiner, Robert A. (2016). Can atorvastatin with metformin change the natural history of prostate cancer as characterized by molecular, metabolomic, imaging and pathological variables? A randomized controlled trial protocol. Contemporary Clinical Trials, 50, 16-20. doi: 10.1016/j.cct.2016.06.014
Roberts, Matthew J., Richards, Renee S., Chow, Clement W. K., Doi, Suhail A. R., Schirra, Horst Joachim, Buck, Marion, Samaratunga, Hemamali, Perry-Keene, Joanna, Payton, Diane, Yaxley, John, Lavin, Martin F. and Gardiner, Robert A. (2016). Prostate-based biofluids for the detection of prostate cancer: a comparative study of the diagnostic performance of cell-sourced RNA biomarkers. Prostate International, 4 (3), 97-102. doi: 10.1016/j.prnil.2016.04.002
Roberts, Matthew J., Chow, Clement W., Schirra, Horst J., Richards, Renee, Buck, Marion, Selth, Luke A., Doi, Suhail A. R., Samaratunga, Hema, Perry-Keene, Joanna, Payton, Diane, Yaxley, John, Lavin, Martin F. and Gardiner, Robert A. (2015). Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer. Prostate, 75 (5), 539-549. doi: 10.1002/pros.22942
Othman, Dk Seti Maimonah Pg, Schirra, Horst, McEwan, Alastair G. and Kappler, Ulrike (2014). Metabolic versatility in Haemophilus influenzae: a metabolomic and genomic analysis. Frontiers in Microbiology, 5 (MAR) 69, 69.1-69.10. doi: 10.3389/fmicb.2014.00069
Li, Juan, Greenwood, Paul L., Cockett, Noelle E., Hadfield, Tracy S., Vuocolo, Tony, Byrne, Keren, White, Jason D., Tellam, Ross L. and Schirra, Horst Joachim (2014). Impacts of the Callipyge mutation on ovine plasma metabolites and muscle fibre type. PLoS One, 9 (6) e99726, e99726.1-e99726.15. doi: 10.1371/journal.pone.0099726
Garvey, Megan, Meehan, Sarah, Gras, Sally L., Schirra, Horst, Craik, David J., Van der Weerden, Nicole L., Anderson, Marilyn A., Gerrard, Juliet A. and Carver, John A. (2013). A radish seed antifungal peptide with a high amyloid fibril-forming propensity. Biochimica et Biophysica Acta: Proteins and Proteomics, 1834 (8), 1615-1623. doi: 10.1016/j.bbapap.2013.04.030
Ormerod, Kate L., Morrow, Carl A., Chow, Eve W. L., Lee, I. Russel, Arras, Samantha D. M., Schirra, Horst Joachim, Cox, Gary M., Fries, Bettina C. and Fraser, James A. (2013). Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence. G3: Genes, Genomes, Genetics, 3 (4), 675-686. doi: 10.1534/g3.113.005660
Abd Rahman, Shaffinaz, Schirra, Horst Joachim, Lichanska, Agnieszka M., Huynh, Tony and Leong, Gary M. (2013). Urine metabonomic profiling of a female adolescent with PIT-1 mutation before and during growth hormone therapy: insights into the metabolic effects of growth hormone. Growth Hormone & IGF Research, 23 (1-2), 29-36. doi: 10.1016/j.ghir.2012.12.001
Hochrein, Jochen, Klein, Matthias S., Zacharias, Helena U., Li, Juan, Wijffels, Gene, Schirra, Horst Joachim, Spang, Rainer, Oefner, Peter J. and Gronwald, Wolfram (2012). Performance evaluation of algorithms for the classification of metabolic 1H-NMR fingerprints. Journal of Proteome Research, 11 (12), 6242-6251. doi: 10.1021/pr3009034
Schlipalius, David I., Valmas, Nicholas, Tuck, Andrew G., Jagadeesan, Rajeswaran, Ma, Li, Kaur, Ramandeep, Goldinger, Anita, Anderson, Cameron, Kuang, Jujiao, Zuryn, Steven, Mau, Yosep S., Cheng, Qiang, Collins, Patrick J., Nayak, Manoj K., Schirra, Horst Joachim, Hilliard, Massimo A. and Ebert, Paul R. (2012). A core metabolic enzyme mediates resistance to phosphine gas. Science, 338 (6108), 807-810. doi: 10.1126/science.1224951
Li, Juan, Schirra, Horst Joachim, Yu, Yihua, Colgrave, Michelle L., Stoermer, Martin J. and Wijffels, Gene (2012). Identification of crotonyl glycine in urine of sheep after 48h road transport. Journal of Pharmaceutical and Biomedical Analysis, 67–68, 129-136. doi: 10.1016/j.jpba.2012.04.028
Morrow, Carl A., Lee, I. Russell, Chow, Eve W. L., Ormerod, Kate L., Goldinger, Anita, Byrnes III, Edmond J., Nielsen, Kirsten, Heitman, Joseph, Schirra, Horst Joachim and Fraser, James A. (2012). A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence. mBio, 3 (2) e00310-11, e00310.1-e00310.11. doi: 10.1128/mBio.00310-11
Xie, Baogang, Waters, Michael J. and Schirra, Horst Joachim (2012). Investigating potential mechanisms of obesity by metabolomics. Journal of Biomedicine and Biotechnology, 2012 (4) 805683, 805683.1-805683.10. doi: 10.1155/2012/805683
Li, Juan, Wijffels, Gene, Yu, Yihua, Nielsen, Lars K., Niemeyer, Dominic O., Fisher, Andrew D., Ferguson, Drewe M. and Schirra, Horst Joachim (2011). Altered fatty acid metabolism in long duration road transport: An NMR-based metabonomics study in sheep. Journal of Proteome Research, 10 (3), 1073-1087. doi: 10.1021/pr100862t
Roberts, Matthew J., Schirra, Horst J., Lavin, Martin F. and Gardiner, Robert A. (2011). Metabolomics: A novel approach to early and noninvasive prostate cancer detection. Korean Journal of Urology, 52 (2), 79-89. doi: 10.4111/kju.2011.52.2.79
Clarke, Raymond A., Schirra, Horst J., Catto, James W., Lavin, Martin F. and Gardiner, Robert A. (2010). Markers for detection of prostate cancer. Cancers, 2 (2), 1125-1154. doi: 10.3390/cancers2021125
Schirra, Horst Joachim, Guarino, Rosemary F., Anderson, Marilyn A. and Craik, David J. (2009). Selective removal of individual disulfide bonds within a potato type II serine proteinase inhibitor from Nicotiana alata reveals differential stabilization of the reactive-site loop. Journal of Molecular Biology, 395 (3), 609-626. doi: 10.1016/j.jmb.2009.11.031
Wang, Conan K., Schirra, Horst Joachim and Craik, David J. (2008). NMRDyn: a program for NMR relaxation studies of protein association. PLoS One, 3 (11) e3820, e3820-1-e3820-7. doi: 10.1371/journal.pone.0003820
Schirra, Horst Joachim, Anderson, Cameron G., Wilson, William J., Kerr, Linda, Craik, David J., Waters, Michael J. and Lichanska, Agnieszka M. (2008). Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study. PLoS One, 3 (7) e2764, e2764-1-e2764-15. doi: 10.1371/journal.pone.0002764
Schirra, H. J., Anderson, M and Craik, D. J. (2008). Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata. Protein and Peptide Letters, 15 (9), 903-909. doi: 10.2174/092986608785849326
Wang, C., Guncar, G., Forwood, J., Teh, T., Catanzariti, A., Lawrence, G., Loughlin, F., Mackay, J., Schirra, H., Anderson, P., Ellis, J., Dodds, P. and Kobe, B. (2007). Crystal structures of flax rust avirulence proteins AvrL567-A and -D reveal details of the structural basis for flax disease resistance specificity. Plant Cell, 19 (9), 2898-2912. doi: 10.1105/tpc.107.053611
Schirra, H. J. and Craik, D. J. (2005). Structure and folding of potato type II proteinase inhibitors: Circular permutation and intramolecular domain swapping. Protein And Peptide Letters, 12 (5), 421-431. doi: 10.2174/0929866054395266
Korsinczky, M. L. J., Schirra, H. J. and Craik, D. J. (2004). Sunflower trypsin inhibitor-1. Current Protein & Peptide Science, 5 (5), 351-364. doi: 10.2174/1389203043379594
Heras, B., Edeling, M. A., Schirra, H. J., Raina, S. and Martin, J. L. (2004). Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide. Proceedings of The National Academy of Sciences of The United States of America, 101 (24), 8876-8881. doi: 10.1073/pnas.0402769101
Marx, Ute C., Korsinczky, Michael L. J., Schirra, Horst Joachim, Jones, Alun, Condie, Barrie, Otvos, Laszlo and Craik, David J. (2003). Enzymatic cyclization of a potent Bowman-Birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide. Journal of Biological Chemistry, 278 (24), 21782-21789. doi: 10.1074/jbc.M212996200
Lay, Fung T., Schirra, Horst Joachim, Scanlon, Martin J., Anderson, Marilyn A. and Craik, David J. (2003). The Three-dimensional Solution Structure of NaD1, a New Floral Defensin from Nicotiana alata and its Application to a Homology Model of the Crop Defense Protein alfAFP. Journal of Molecular Biology, 325 (1), 175-188. doi: 10.1016/S0022-2836(02)01103-8
Janssen, Bert J. C., Schirra, Horst Joachim, Lay, Fung T., Anderson, Marilyn A. and Craik, David J. (2003). Structure of Petunia hybrida Defensin 1, a Novel Plant Defensin with Five Disulfide Bonds. Biochemistry, 42 (27), 8214-8222. doi: 10.1021/bi034379o
Korsinczky, M. L. J., Schirra, H. J., Rosengren, K. J., West, J., Condie, B. A., Otvos, L., Anderson, M. A. and Craik, D. J. (2001). Solution structures by H-1 NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant. Journal of Molecular Biology, 311 (3), 579-591. doi: 10.1006/jmbi.2001.4887
Schirra, H. J., Scanlon, M. J., Lee, M. C. S., Anderson, M. A. and Craik, D. J. (2001). The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata. Journal of Molecular Biology, 306 (1), 69-79. doi: 10.1006/jmbi.2000.4318
Trabi, M., Schirra, H. J. and Craik, D. J. (2001). Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from rhesus macaque leukocytes. Biochemistry, 40 (14), 4211-4221. doi: 10.1021/bi002028t
Schirra, HJ, Renner, C, Czisch, M, Huber-Wunderlich, M, Holak, TA and Glockshuber, R (1998). Structure of reduced DsbA from Escherichia coli in solution. Biochemistry, 37 (18), 6263-6276. doi: 10.1021/bi980136y
Conference Papers
Fyfe, Selina, Schirra, Horst Joachim, Rychlik, Michael, van Doorn, Anne Marie, Tinngi, Ujang, Sultanbawa, Yasmina and Smyth, Heather E. (2022). Future flavours from the past: sensory analysis of fruits from Arnhem Land. International Agriculture Conference (TropAg 2022), Brisbane, QLD Australia, 31 October - 2 November 2022.
Fyfe, Selina, Hong, Hung, Schirra, Horst Joachim, Smyth, Heather E., Sultanbawa, Yasmina and Rychlik, Michael (2022). Folate vitamers of the native Australian green plum (Buchanania obovata). International Agriculture Conference (TropAg 2022), Brisbane, QLD Australia, 31 October - 2 November 2022.
Hungerford, Natasha L., Zhang, Jiali, Smith, Tobias J., Carpinelli de Jesus, Matheus, Yates, Hans S. A., Chowdhury, Sadia A., Carter, James F., Webber, Dennis, Stone, Isobella S. J., Blanchfield, Joanne T., Zawawi, Norhasnida, Schirra, Horst J., Tran, Trong D. and Fletcher, Mary T. (2021). Stingless bees produce honey rich in the beneficial disaccharide, trehalulose. Symposium of Research & Innovation for Food (SoRIF), Universiti Teknologi MARA, Malaysia via WebEX, 23-24 June 2021.
Fyfe, Selina, Sultanbawa, Yasmina, Schirra, Horst Joachim, Rychlik, Michael and Smyth, Heather E. (2021). Sensory profiling of summer fruit from East Arnhem Land. The 15th NZOZ Sensory and Consumer Science Symposium, A Virtual Conference, 9-11 February 2021. New Zealand:
Fyfe, Selina, Smyth, Heather E., Schmitt-Kopplin, Philippe, Rychlik, Michael, Sultanbawa, Yasmina and Schirra, Horst Joachim (2020). The nutritional potential of the Australian Green Plum (Buchanania obovata). Metabolomics 2020: The 16th Annual Conference of the Metabolomics Society, Online, 27 - 29 October 2020.
Chow, C., Schirra, H., Yaxley, J., Lavin, M., Roberts, M., Richards, R. and Gardiner, R. (2018). An investigation using molecular and metabolomic biomarkers for the non-invasive detection and characterisation of prostate cancer. 71st Annual Scientific Meeting of the Urological-Society-of-Australia-and-New-Zealand, Melbourne Australia, 24-27 February 2018. Hoboken, NJ United States: Wiley.
Roberts, Matthew J., Richards, Renee S. Stirling, Chow, Clement W., Buck, Marion, Yaxley, John W., Lavin, Martin F., Schirra, Horst Joachim J. and Gardiner, Robert ('Frank') (2017). Non-invasive selection and monitoring of active surveillance candidates using NMR-based metabolomics: a preliminary investigation of seminal plasma. ANZUP Annual Scientific Meeting: The Art & Science of Best Practice, Melbourne, Australia, 16-18 July 2017. Chichester, West Sussex, United Kingdom: Wiley-Blackwell .
Roberts, Matthew J., Richards, R., Chow, C. W. K., Schirra, H., Buck, M., Selth, L. A., Doi, S. A., Samaratunga, H., Perry-Keene, J., Payton, D., Yaxley, J., Lavin, M. F. and Gardiner, R. A. (2016). Prostatic fluid mRNA and microRNA biomarkers: an emerging paradigm for noninvasive diagnosis of prostate cancer. ANZUP Annual Scientific Meeting, GU Cancer: Expanding our Horizons, Brisbane, QLD Australia, 10-12 July 2016. Chichester, West Sussex United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12558
Roberts, M., Chow, C., Schirra, H., Richards, R., Buck, M., Doi, S., Samaratunga, H., Yaxley, J., Lavin, M. and Gardiner, R. (2016). A new prostate-based biofluid for the detection of prostate cancer and diagnostic performance comparison using mRNA biomarkers. 69th Annual Scientific Meeting of the Urological-Society-of-Australia-and-New Zealand, Gold Coast, Australia, 16-19 April 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/bju.13452
Roberts, Chow, Schirra, Richards, Buck, Seth, Doi, Samaratunga, Perry-Keene, Payton, Yaxley, Lavin and Gardiner (2015). Diagnostic performance of PCA3, Hepsin and microRNA biomarkers in ejaculate in combination with serum PSA for the detection and triaging of prostate cancer. 68th Annual Scientific Meeting of the Urological-Society-of-Australia-and-New Zealand, Adelaide, AUSTRALIA, APR 11-14, 2015. HOBOKEN: WILEY-BLACKWELL.
Roberts, M., Teng, L., Buck, M., Schirra, H., Hancock, J., Clarke, R., Samaratunga, H., Zenzmaier, C., Lavin, M. and Gardiner, R. (2012). Molecular and metabonomic ejaculate profiling enables prostate cancer detection. 65th Annual Scientific Meeting on Urological Society of Australia and New Zealand, Darwin, NT, Australia, 21-24 April 2012. Oxford England U.K.: Wiley-Blackwell Publishing. doi: 10.1111/j.1464-410X.2012.11074.x
Roberts, M. J., Schirra, H. J., Teng, L., Lavin, M. F. and Gardiner, R. A. (2011). Prostate cancer metabolomics: An emerging method of screening and diagnosis. Australian Society for Medical Research Queensland Postgraduate Student Conference, Brisbane, Australia, 31 May 2011.
Gardiner, R. A., Teng, L., Buck, M., Hancock, J., Clarke, R., Samaratunga, H., Schirra, H. J., Zenzmaier, C., Berger, P., Catto, J., Yaxley, J., Gianduzzo, T., Coughlin, G. and Lavin, M. F. (2011). Multiple markers in prostate cancer detection from ejaculate. 64th Annual Scientific Meeting of the Urological Society of Australia and New Zealand, Christchurch, New Zealand, 21-24 February 2011. Oxford, U.K.: Wiley-Blackwell Publishing. doi: 10.1111/j.1464-410X.2011.9997.x
Roberts M. J., Schirra H. J., Lavin M. F. and Gardiner R. A. (2011). This won’t hurt a bit – NMR-based metabolomics in medical diagnosis of prostate cancer. ANZMAG-2011 – the Australian and New Zealand Society for Magnetic Resonance, Torquay, Victoria, 12th October 2011.
Schirra, H. J., Roberts, M. J., Lavin, M. F. and Gardiner, R. A. (2011). This won’t hurt a bit – NMR-based metabolomics in medical diagnosis of prostate cancer. 7th International Conference of the Metabolomics Society, Cairns, Australia, 27 - 30 June 2011.
Roberts, M. J., Schirra, H. J., Teng, L., Lavin, M. F. and Gardiner, R. A. (2011). Urine and ejaculate link local pathophysiology with systemic metabolic changes in Prostate Cancer: A metabolomic study. 12th Australasian Prostate Cancer Conference 2011, Melbourne, Australia, 3 - 5 August 2011.
Fuerst, John A., Hewavitharana, Amitha, Hooper, John, Izumi, Hiroshi, Ng, Yi Kai, Sagulenko, Evgeny, Shaw, Paul N., Schirra, Horst and Vidgen, Miranda (2011). Salinispora, Planctomycetes and their implications for sponge microbiology. 1st International sponge microbiology conference, Germany, 2011.
Gardiner, R. A., Buck, M., Teng, L., Schirra, H. J., Roberts, M. J., Zenzmaier, C., Hancock, J., O'Rourke, P., Samaratunga, M. L. T. H., Scells, B., Payton, J. D., Perry-Keene, J., Yaxley, J., Coughlin, G. and Lavin, M. F. (2011). Multiple markers in prediction of prostate cancer from ejaculate. 20th Annual RBWH Health Care Symposium: Personalised Health Care, Brisbane, Australia, 10 -14 October 2011.
Roberts, M. J., Schirra, H. J., Teng, L., Lavin, M. F. and Gardiner, R. A. (2011). Prostate cancer metabolomics: Novel, robust, promising. 3rd UQMS Research Colloquium, Brisbane, Australia, 15th August 2011.
Schirra, Horst, Abd Rahman, S., Leong, G. M., Nielsen, L. K. and Waters, M. J. (2010). Of mice and men - NMR-based metabonomics between systems biology and clinical science. 2nd Australasian Symposium on Metabolomics, Melbourne, Australia, 30 September - 5 October 2010.
Abd-Rahman, Shaffinaz, Leong, Gary M. and Schirra, Horst J. (2010). NMR metabonomics: Method development and applications in obesity and related diseases. 23rd International Conference on Magnetic Resonance in Biological Systems, Cairns, QLD, Australia, 22-27 August 2010.
Li, J., Wijffels, G., Ferguson, D. M., Hunt, P. and Schirra, H.J. (2010). The passionate shepherd to his sheep - NMR-based metabonomics in animal welfare. 23rd International Conference on Magnetic Resonance in Biological Systems, Cairns, Australia, 22-27 August, 2010.
Schirra, H. J., Abd Rahman, S., Leong, G. M., Nielsen, L. K. and Waters, M. J. (2010). Of mice and men - NMR-metabonomics between systems biology and clinical science. 23rd International Conference on Magnetic Resonance in Biological Systems, Cairns, Australia, 22-27 August 2010.
Teng, L., Buck, M., Hancock, J., Clarke, R., Samaratunga, H., Schirra, H., Zenzmaier, C., Berger, P., Catto, J., Yaxley, J., Gianduzzo, T., Coughlin, G., Lavin, M. and Gardiner, R. (2010). Multiple markers in prostate cancer detection in ejaculate. URS, USANZ Meeting 2010, Nelson, New Zealand, 10-12 November, 2010.
Schirra, H.J., Abd-Rahman, S., Wijffels, G, Ferguson, D., Leong, G.M., Waters, M.J. and Lichanska, A.M. (2010). Of mice and men - NMR-based metabonomics from animal systems to clinical science. Metabolomics and More - 1st International Metabolomics Symposium in Germany, Freising, Germany, 10-12 March, 2010.
Abd Rahman, S., Leong, G. M. and Schirra, H. J. (2010). NMR metabonomics method development and applications in obesity and related diseases. Metabolomics and More - 1st International Metabolomics Symposium in Germany, Freising, Germany, 10-12 March 2010.
Li, J., Wijffels, G., Colgrave, M., Stoermer, M.J. and Schirra, H.J. (2010). Identification of crotonyl glycine in sheep urine using RP-HPLC, NMR and ESI-MS. Metabolomics and More - 1st International Metabolomics Symposium in Germany, Freising, Germany, 10-12 March, 2010.